Transporters in Drug Discovery and Development: Detailed Concepts and Best Practice (Hardcover) by Yurong Lai

ISBN: 9781907568213 Condition: New Hard cover Language: English Pages: 780 Sewn binding. Cloth over boards. 780 p. Woodhead Publishing Biomedicine. Written by a leading researcher in the field, Transporters in Drug Discovery and Development provides a comprehensive and practical guide to drug transporter families that are the most important for drug discovery and development. It covers: an overview of transporter families and organ distribution; clinical relevant drug-drug interaction; clinical relevant polymorphism; drug transporter related pharmacokinetic, pharmacodynamics and toxicity; in vitro/in vivo probes of drug transport studies; the practical methodologies of industrial transporter screening and translational aspect in drug discovery and developments.