Raza Asad: Analysis of Lisinopril and Tranexamic Acid Tablets(Paperback)

Raza Asad: Analysis of Lisinopril and Tranexamic Acid Tablets(Paperback) Describes two simple, fast, accurate, and sensitive spectrophotometric methods for determining Lisinopril and Tranexamic acid in pharmaceutical preparations First method utilizes ninhydrin reaction with primary amine in Lisinopril in DMF solvent, producing a bluish green color that absorbs maximally at 600 nm Beer's law is obeyed in the concentration range of 10-150 µg/ml with a molar absorptivity of 4.083 × 10³ Lmole⁻¹cm⁻¹ Second method involves ninhydrin reaction with primary amine of Tranexamic acid in a basic medium at pH 8, resulting in a blue color that absorbs maximally at 565 nm Beer's law is obeyed in the concentration range of 3-40 µg/ml with a molar absorptivity of 5.093 × 10³ Lmole⁻¹cm⁻¹ Investigates the effects of variables such as temperature, heating time, reagent concentration, and color stability to optimize procedures Results are statistically valid and applicable for determining Lisinopril and Tranexamic acid in pharmaceutical preparations with good results